Sean’s paper is out in Molecular Systems Biology
Using light to shape chemical gradients for parallel and automated analysis of chemotaxis.
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Systematic Discovery of Human Gene Function and Principles of Modular Organization through Phylogenetic Profiling.
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Dynamic recruitment of the curvature-sensitive protein ArhGAP44 to nanoscale membrane deformations limits exploratory filopodia initiation in neurons.
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A polarized Ca2+, diacylglycerol and STIM1 signalling system regulates directed cell migration.
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Protein concentrations are often regulated by dynamic changes in translation rates. Nevertheless, it has been challenging to directly monitor changes in translation in living cells....
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Mammalian cells have a remarkable capacity to compensate for heterozygous gene loss or extra gene copies. One exception is Down syndrome (DS), where a third copy of chromosome 21 mediates neurogenesis defects and lowers the frequency of solid tumors...
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Tissue homeostasis in metazoans is regulated by transitions of cells between quiescence and proliferation.
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