The Meyer lab seeks to understand how human cells sense hormones, growth factors, cell contacts and stress and how they integrate and transduce these signals to make decisions to polarize, move or divide. We investigate these cellular regulatory systems by identifying key signaling components and measure when and where signaling occurs by using live-cell microscopy approaches to watch cells signal and decide to move forward or enter the cell cycle. Our projects are focused on understanding the general principles of how mammalian signal transduction systems work which requires the development and application of new experimental and analysis tools including advanced fluorescent microscopy techniques, small molecule and light perturbations, systematic genomic and targeted screens, RNAseq technologies, bioinformatics, organoids and other in vitro and in vivo models, and quantitative modeling of signaling pathways.
Transient Hysteresis in CDK4/6 Activity Underlies Passage of the Restriction Point in G1
The Lab went to the California Clasico at Stanford Stadium to watch the San Jose Earthquakes defeat the LA Galaxy 2-0!
Putting the brakes on the cell cycle: mechanisms of cellular growth arrest
The Meyer Lab ventured to Campo di Bocce in Los Gatos to celebrate Min's time in the lab!
Chemical and Systems Biology
318 Campus Drive, Clark Building W200
Stanford University Medical Center Stanford
(650) 723 9819